2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125850R
    Berberrubine chloride (Standard)
    Berberrubine (chloride) (Standard) is the analytical standard of Berberrubine (chloride). This product is intended for research and analytical applications. Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model.
    Berberrubine chloride (Standard)
  • HY-W086896R
    α-Demethylnaproxen (Standard)
    α-Demethylnaproxen (Standard) is the analytical standard of α-Demethylnaproxen. This product is intended for research and analytical applications. α-Demethylnaproxen is the major metabolite of Nabumetone (HY-B0559), Nabumetone is an orally active COX-2 inhibitor with anti-inflammatory activity.
    α-Demethylnaproxen (Standard)
  • HY-G0012S
    Monohydroxy Netupitant-d6
    Monohydroxy Netupitant-d6 is the deuterium labeled Monohydroxy Netupitant, which is a metabolite of Netupitant.
    Monohydroxy Netupitant-d<sub>6</sub>
  • HY-135731R
    4-Methylamino antipyrine (Standard)
    4-Methylamino antipyrine (Standard) is the analytical standard of 4-Methylamino antipyrine. This product is intended for research and analytical applications. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties.
    4-Methylamino antipyrine (Standard)
  • HY-10873S2
    N-Desethyl Sunitinib-d5 hydrochloride
    N-Desethyl Sunitinib-d5 (hydrochloride) is a deuterated labeled N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively.
    N-Desethyl Sunitinib-d<sub>5</sub> hydrochloride
  • HY-G0012
    Netupitant metabolite Monohydroxy Netupitant
    Monohydroxy Netupitant is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.
    Netupitant metabolite Monohydroxy Netupitant
  • HY-128379R
    Labetalone hydrochloride (Standard)
    Labetalone (hydrochloride) (Standard) is the analytical standard of Labetalone (hydrochloride). This product is intended for research and analytical applications. Labetalone hydrochloride is an impurity of Labetalol. Labetalol is an orally active adrenoceptor blocking agent which is a competitive antagonist at both alpha- and beta-adrenoceptor sites.
    Labetalone hydrochloride (Standard)
  • HY-130189R
    S-Phenylmercapturic acid (Standard)
    S-Phenylmercapturic acid (Standard) is the analytical standard of S-Phenylmercapturic acid. This product is intended for research and analytical applications. S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay.
    S-Phenylmercapturic acid (Standard)
  • HY-W740216
    N-Demethyl Mifepristone
    N-Demethyl Mifepristone (RU 42633) is an active metabolite of Mifepristone (HY-13683). The affinities of N-Demethyl Mifepristone to the glucocorticoid receptor is 61% compared with 100% for Mifepristone.
    N-Demethyl Mifepristone
  • HY-G0010
    Netupitant metabolite N-desmethyl Netupitant
    N-desmethyl Netupitant is a metabolite of Netupitant, which is an antiemitic drug.
    Netupitant metabolite N-desmethyl Netupitant
  • HY-119223
    Desmethylmirtazapine
    Desmethylmirtazapine is an active metabolite of Mirtazapine that has antidepressant effects.
    Desmethylmirtazapine
  • HY-126857R
    5-Hydroxyomeprazole (Standard)
    5-Hydroxyomeprazole (Standard) is the analytical standard of 5-Hydroxyomeprazole. This product is intended for research and analytical applications. 5-Hydroxyomeprazole is the major metabolite of Omeprazole (HY-B0113).
    5-Hydroxyomeprazole (Standard)
  • HY-G0002
    Lurasidone metabolite 14326
    		Chemical
    Lurasidone metabolite 14326 is an active metabolite of the atypical antipsychotic Lurasidone.
    Lurasidone metabolite 14326
  • HY-114992
    2-Propyl-2-pentenoic acid
    2-Propyl-2-pentenoic acid is a metabolite of Valproic acid (HY-10585). 2-Propyl-2-pentenoic acid has a facilitating action on the acquisition of conditioned behavior with negative reinforcement in mice.
    2-Propyl-2-pentenoic acid
  • HY-G0014S
    Quetiapine Sulfoxide-d8
    Quetiapine Sulfoxide-d8 is the deuterium labeled Quetiapine sulfoxide. Quetiapine sulfoxide (Quetiapine S-oxide) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[1][2].
    Quetiapine Sulfoxide-d<sub>8</sub>
  • HY-138128
    Acetaminophen mercapturate
    Acetaminophen mercapturate is a metabolite of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor.
    Acetaminophen mercapturate
  • HY-W700620
    Hydroxymethyl dasatinib
    Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib (HY-10181), exhibits an IC50 of 46.7nM in K562 CML cells.
    Hydroxymethyl dasatinib
  • HY-131273R
    Febuxostat amide impurity (Standard)
    Febuxostat amide impurity (Standard) is the analytical standard of Febuxostat amide impurity. This product is intended for research and analytical applications. Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM
    Febuxostat amide impurity (Standard)
  • HY-135577R
    β-Apooxytetracycline (Standard)
    β-Apooxytetracycline (Standard) is the analytical standard of β-Apooxytetracycline. This product is intended for research and analytical applications. β-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is a widespread antibiotic.
    β-Apooxytetracycline (Standard)
  • HY-137769R
    Captopril EP Impurity C (Standard)
    Captopril EP Impurity C (Standard) is the analytical standard of Captopril EP Impurity C. This product is intended for research and analytical applications. Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity C (Standard)
Cat. No. Product Name / Synonyms Application Reactivity